RAD 140 (Testolone)

Overview of RAD-140

RAD-140 (Testolone) is a synthetic selective androgen receptor modulator (SARM). Researchers utilized it as a reference material for analytical and laboratory research applications. Its characterization is limited to controlled experimental settings for the evaluation of receptor-binding properties and related biochemical activity. 

Chemical and Molecular Properties 

RAD-140
PubChem CID	44200882
Molecular Formula	C19H17N3O
Molecular Weight	303.4 g/mol
Synonyms	RAD140 Vosilasarm Testolone RAD-140
IUPAC	2-chloro-4-[[(1R,2S)-1-[5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl]-2-hydroxypropyl]amino]-3-methylbenzonitrile
CAS	1182367-47-0
Labeling	Research Use Only (RUO), not for human or animal consumption.
Chemical Structure Depiction
Purity	≥98%
Classification	Research Use Only (RUO)
Storage Temperature	Lyophilized: –20 °C or colder
Solubility	Soluble in DMSO, ethanol, and polyethyl glycol (PEG); limited water solubility
Safety	Handle with gloves, a lab coat, and eye protection; use a fume hood if dust/aerosol is possible

Proposed Working Mechanism of RAD-140

Researchers have observed that RAD-140 (Testolone) may interact with androgen receptors located in cellular systems in preclinical research models. Upon binding, it forms a receptor–ligand complex that translocates to the nucleus. 

This complex binds to androgen response elements on DNA and modulates transcriptional activity of androgen-responsive genes, as observed by research experts.

The resulting activity alters gene expression patterns associated with protein synthesis and protein degradation pathways. Researchers believe this may happen through receptor-mediated transcriptional regulation and downstream signaling cascades.

Why Choose Purerawz for RAD-140?

Buy RAD-140 for laboratory research use from our online shop. At Purerawz, we provide high-quality reference materials. Each research compound comes with a Certificate of Analysis for verification of purity and concentration.

Note:

RAD-140 is an investigational compound. It is not established as safe or effective for any therapeutic use.

Disclaimer

This information is for educational purposes only and not medical advice. Products are for research use only. Research must follow IRB or IACUC guidelines. Verify information independently before purchasing. By ordering, you agree to our Terms and Conditions. If you are not 100% satisfied with the product you received, please contact us at support@purerawz.co

ATTENTION: All our products are for LABORATORY AND RESEARCH PURPOSES ONLY, not for veterinary or human use

Reference Links

• PubChem. (n.d.). 2-Chloro-4-(((1R,2S)-1-(5-(4-cyanophenyl)-1,3,4-oxadiazol-2-yl)-2-hydroxypropyl)amino)-3-methylbenzonitrile – RAD-140 (Testolone). PubChem Compound Database. U.S. National Library of Medicine. https://pubchem.ncbi.nlm.nih.gov/compound/44200882
• Miller, C. P., Dalton, J. T., & Reiser, P. J. (2010). Design, synthesis, and preclinical characterization of the selective androgen receptor modulator RAD140. ACS Medicinal Chemistry Letters, 2(2), 124–129. https://pubs.acs.org/doi/10.1021/ml1002508 
• Narayanan, R., et al. (2011). Selective androgen receptor modulators: Mechanistic insights and preclinical frameworks. Journal of Steroid Biochemistry and Molecular Biology. https://pubmed.ncbi.nlm.nih.gov/19079612/