Enclomiphene Citrate + Pregnanolone Stack

The Enclomiphene Citrate + Pregnanolone Stack is for lab and research use only. This stack is being researched to understand how hormone balance and brain function interact in areas such as the health of male subjects, testosterone production, and mental wellness.

Enclomiphene, a selective estrogen receptor modulator (SERM) for testosterone regulation, and Pregnanolone, a neurosteroid for central nervous system activity.

This stack is now available in PureRawz. This is not FDA-approved. This must be used in research settings only. It is in tablet form for more convenient use in lab work.

What Is Enclomiphene Citrate?

Enclomiphene Citrate is a known SERM. It is used in fertility research. It stimulates the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) by inhibiting estrogen receptors in the pituitary and hypothalamus.

Current research is looking into Enclomiphene’s role in secondary hypogonadism, testosterone restoration, and sperm production.

Enclomiphene has not been FDA-approved. The development of male hypogonadism was halted. It remains an investigational compound.

Chemical Information:

Product Name:	Enclomiphene
CAS Number:	15690-57-0.
Molar Mass:	405.97 g/mol.
Chemical Formula:	C26H28ClNO
IUPAC Name:	2-[4-[(E)-2-chloro-1,2-diphenylethenyl]phenoxy]-N,N-diethylethanamine

What Is Pregnanolone?

Pregnanolone (3a-hydroxy-5B-pregnan-20-one) is a naturally occurring neurosteroid derived from progesterone, often referred to as a “mother hormone” for other steroid hormones. It interacts mainly with GABA-A receptors in the brain, mood regulation, sleep, and stress response.
Research is looking into cognitive decline, mental health, and neuroprotection.

Chemical Information:

Product Name:	Pregnanolone
CAS Number:	128-20-1
Molar Mass:	318.49 g/mol
Chemical Formula:	C21H32O2
IUPAC Name:	1-[(3S,8S,9S,10R,13S,14S,17S)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl]ethanone

What are its Research Benefits?

These are early and pre-clinical studies only.

May increase natural testosterone in male subjects with low levels.
Useful in studying hormone balance through the pituitary gland and hypothalamus.
Can study sperm production and fertility mechanisms.
In research, Pregnanolone may show calming or neuroprotective effects in test models.
May explore alternatives to hormone replacement or testosterone therapy.

How Does It Work?

Enclomiphene Citrate: Works as a selective estrogen receptor modulator, blocking estrogen’s inhibitory effect on the pituitary gland. This leads to increased luteinizing hormone (LH) and follicle-stimulating hormone (FSH), which can stimulate the testes to produce testosterone naturally in research models.

Pregnanolone: Acts as a positive allosteric modulator of GABA-A receptors, enhancing inhibitory neurotransmission in the brain. This may contribute to calming effects, mood stability, and cognitive performance in test subjects.

What are its Side Effects?

This stack is not for medical use. Human safety profiles are not fully described and vary depending on research use.

Enclomiphene: Mild headaches, nausea, or mood changes.
Pregnanolone: Dizziness, fatigue, or drowsiness.

Disclaimer

This information is for educational and research purposes only. It does not constitute a medical or treatment recommendation. All products from PureRawz are for laboratory use only and not for human consumption. If you have any concerns about the product. Reach out to support@purerawz.co