T3 Liothyronine Sodium + 5a-Hydroxy Laxogenin + SR-9011 + GW-0742 + Yohimbine Transdermal

T3 Liothyronine Sodium + 5a-Hydroxy Laxogenin + SR-9011 + GW-0742 + Yohimbine Transdermal – Product Information

T3 Liothyronine Sodium + 5a-Hydroxy Laxogenin + SR-9011 + GW-0742 + Yohimbine Transdermal is a research compound designed to explore the potential effects of its unique combination of T3 Liothyronine Sodium, 5a-Hydroxy Laxogenin, SR-9011, GW-0742, and Yohimbine. This formulation has a collective impact on various aspects of lipid metabolism and energy regulation in preclinical models. 

The Ultimate Transdermal is strictly intended for research purposes.

• The Transdermal consists of T3 Liothyronine Sodium, 5a-Hydroxy Laxogenin, SR-9011, GW-0742, and Yohimbine.
• The Transdermal is offered as 50mcg T3 Liothyronine Sodium, 7.5mg 5a-Hydroxy Laxogenin, 5mg SR9011, 5mg GW0742, and 2.5mg Yohimbine, totaling 20mg per ml for 60ml or 1200mg in total.

T3 Liothyronine Sodium

Thyroid hormones, specifically T3 Liothyronine Sodium, have garnered interest in research due to their potential interactions with fat mass. A recent study conducted on rats explored the effects of T3 supplementation and found that it did not abolish the increased expression of thyroid hormone receptor beta, which occurs during caloric restriction. Additionally, T3 supplementation led to increased leptin gene expression.

The data suggest that T3 may not significantly elevate metabolic rate but rather mitigate the decline typically observed during prolonged caloric restriction in research models.

T3 Liothyronine Sodium Liquid
CAS Number	6893-02-3
Molar Mass	650,9735 g/mol
Chemical Formula	C15H12I3NO4
IUPAC Name	sodium;(2S)-2-amino-3-[4-(4-hydroxy-3-iodophenoxy)-3,5-diiodophenyl]propanoate 5a-Hydroxy Laxogenin

5a-Hydroxy Laxogenin

Laxogenin, also known as 5 alpha hydroxy laxogenin or 5a hydroxy laxogenin, is a compound derived from plants and belongs to a group of compounds called brassinosteroids. While the exact mechanism of its effects is not yet fully understood, as a brassinosteroid, preliminary studies suggest its potential impact on increasing protein synthesis and reducing protein breakdown.

It is investigated for potential effects on protein synthesis and cortisol modulation in preclinical studies. Despite ongoing research, further investigation is needed to fully elucidate the mechanisms and potential benefits of laxogenin. It is important to note that this information is strictly related to research purposes.

5a-Hydroxy Laxogenin
CAS Number	56786-63-1
Molar Mass	446.6 g/mol
Chemical Formula	C27H42O
IUPAC Name	(1S,2S,4S,5’R,6R,7S,8R,9S,12S,13R,16S,18R)-16,18-dihydroxy-5′,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.02,9.04,8.013,18]icosane-6,2′-oxane]-19-one

SR-9011

A recent study conducted on diet-induced obese mice investigated the effects of SR-9009 and SR-9011, administered twice daily for 30 days. The findings revealed a significant reduction in fat mass and notable improvements in dyslipidemia and hyperglycemia. Activation of REV-ERB, induced by these compounds, was observed to enhance the circadian rhythm in mice, impacting various aspects such as behavior, sleep cycles, and functions associated with increased energy production. These results offer valuable insights into the potential of SR9009 and SR-9011 in addressing obesity-related issues and optimizing metabolic function. It is important to note that this study was conducted for research purposes only.

SR-9011
CAS Number	1379686-29-9
Molar Mass	479.04 g/mol
Chemical Formula	C23H31ClN4O3S
IUPAC Name	3-[[(4-chlorophenyl)methyl-[(5-nitrothiophen-2-yl)methyl]amino]methyl]-N-pentylpyrrolidine-1-carboxamide

GW-0742

GW-0742 is a PPARβ/δ agonist, which is being dubbed as a ‘Super Cardarine’. Studies have shown that GW0742 has the ability to improve glucose homeostasis and increase insulin sensitivity in diabetic rats. In diabetic rats fed a high fructose diet, a group given GW0742 showed lower blood sugar compared to the control group. 

Due to GW0742 being a PPAR agonist, it showed the potential to be studied in research models for its effects on energy metabolism and fat utilization. This has been studied in research models for potential effects on energy metabolism and oxidative capacity in muscle tissue.

GW0742
CAS Number	317318-84-6
Molar Mass	471.48 g/mol
Chemical Formula	C21H17F4NO3S2
IUPAC Name	2-[4-[[2-[3-fluoro-4-(trifluoromethyl)phenyl]-4-methyl-1,3-thiazol-5-yl]methylsulfanyl]-2-methylphenoxy]acetic acid

Yohimbine

Yohimbine is a compound derived from the bark of the Yohimbe tree (Pausinystalia yohimbe) and is of interest in research fields. It is classified as an alpha-2 adrenergic receptor antagonist, which means it blocks the action of these receptors. Yohimbine has been studied for its potential effects on various physiological processes. Preclinical studies show Yohimbine’s cardiovascular and adrenergic responses, and its potential to promote lipolytic activity in preclinical models.

 

Yohimbine
CAS Number	146-48-5
Molar Mass	354.450 g/mol
Chemical Formula	C21H26N2O3
IUPAC Name	17α-hydroxy-yohimban-16α-carboxylic acid methyl ester Disclaimer

Disclaimer

This information is for educational purposes only and does not constitute medical advice. THE PRODUCTS DESCRIBED HEREIN ARE FOR LABORATORY AND RESEARCH USE ONLY. All clinical research must be conducted with oversight from the appropriate Institutional Review Board (IRB). All preclinical research must be conducted with oversight from the appropriate Institutional Animal Care and Use Committee (IACUC), following the guidelines of the Animal Welfare Act (AWA).

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